Instructions: Enter a binding site record in Transfac format or select from samples below. When done, click on the SUBMIT button. The script will extract individual data elements from your input.

BINDING SITE ENTRY:

Sample Input:

AC R00001 XX ID HS$6-16_01 XX DT 20.06.90 (created); ewi. DT 24.08.95 (updated); hiwi. XX TY D XX DE 6-16; Gene: G000176. XX SQ gGGAAAaTGAAACT. XX EL ISRE XX SF -127 ST -89 XX BF T00428; ISGF-3;Quality: 6; Species: human, Homo sapiens. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; OC tetrapoda; mammalia; eutheria; primates XX SO 0038; Bristol 8B+ SO 0061; Daudi SO 0101; HeLa+ SO 0108; HFF SO 0380; Daudi + CML XX MM gel retardation MM methylation protection MM ethylation interference MM methylation interference MM copper/phenanthroline footprinting XX CC human foreskin fibroblasts (HFF) after induction with IFN-alpha XX DR EMBL: Y00828; HSIFNIN6(492:505). DR EPD: E27009; EP027009. XX RN [1] RA Seong D. C., Sims S., Johnson E., Howard O. M. Z., RA Reiter B., Hester J., Talpaz M., Kantarjian H., Deisseroth A. RT A phosphatase activity present in peripheral blood RT myeloid cells of chromic myelogenous leukemia patients RT but not normal individuals alters nuclear protein RT binding to transcriptional enhancers of interferon-inducible genes RL J. Clin. Invest. 86:1664-1670 (1990). RN [2] RA Imam A. M. A., Ackrill A. M., Dale T. C., Kerr I. M., Stark G. R. RT Transcription factors induced by interferons alpha and gamma RL Nucleic Acids Res. 18:6573-6580 (1990). RN [3] RA Roy Ch., Lebleu B. RT DNA protein interactions at the interferon-responsive RT promoter elements: potential for a H-DNA conformation RL Nucleic Acids Res. 19:517 (1991). RN [4] RA Porter A. C. G., Chernajowski Y., Dale T. C., Gilbert RA C. S., Stark G. R., Kerr I. M. RT Interferon response element of the human gene 6-16 RL EMBO J. 7:85-92 (1988). RN [5] RA Dale T. C., Ali Imam A. M., Kerr I. M., Stark G. R. RT Rapid activation by interferon alpha of a latent DNA-binding RT protein present in the cytoplasm of untreated cells RL Proc. Natl. Acad. Sci. USA 86:1203-1207 (1989). RN [6] RA Dale T. C., Rosen J. M., Guille M. J., Lewin A. R., RA Porter A. G. C., Kerr I. M., Stark G. R. RT Overlapping sites for constitutive and induced DNA RT binding factors involved in interferon-stimulated transcription RL EMBO J. 8:831-839 (1989). XX //

More Sample Inputs: Click on an Acc No. to view contents. (Not yet operational.)